Chr10.g71867

Functional evidence

eggNOG

4432.XP_010268829.1,IT,[sphingosine kinase]

Gene Ontology

sphingosine kinase | GO:0001101//response to acid chemical; GO:0001558//regulation of cell growth; GO:0001932//regulation of protein phosphorylation; GO:0001934//positive regulation of protein phosphorylation; GO:0001959//regulation of cytokine-mediated signaling pathway; GO:0003376//sphingosine-1-phosphate signaling pathway; GO:0006066//alcohol metabolic process; GO:0006355//regulation of transcription, DNA-templated; GO:0006457//protein folding; GO:0006629//lipid metabolic process; GO:0006643//membrane lipid metabolic process; GO:0006665//sphingolipid metabolic process; GO:0006670//sphingosine metabolic process; GO:0006793//phosphorus metabolic process; GO:0006796//phosphate-containing compound metabolic process; GO:0006807//nitrogen compound metabolic process; GO:0006937//regulation of muscle contraction; GO:0006940//regulation of smooth muscle contraction; GO:0007154//cell communication; GO:0007165//signal transduction; GO:0007186//G-protein coupled receptor signaling pathway; GO:0007275//multicellular organism development; GO:0007346//regulation of mitotic cell cycle; GO:0008150//biological_process; GO:0008152//metabolic process; GO:0008284//positive regulation of cell proliferation; GO:0008610//lipid biosynthetic process; GO:0009056//catabolic process; GO:0009058//biosynthetic process; GO:0009719//response to endogenous stimulus; GO:0009725//response to hormone; GO:0009737//response to abscisic acid; GO:0009791//post-embryonic development; GO:0009845//seed germination; GO:0009889//regulation of biosynthetic process; GO:0009893//positive regulation of metabolic process; GO:0009966//regulation of signal transduction; GO:0009967//positive regulation of signal transduction; GO:0009987//cellular process; GO:0010033//response to organic substance; GO:0010468//regulation of gene expression; GO:0010556//regulation of macromolecule biosynthetic process; GO:0010562//positive regulation of phosphorus metabolic process; GO:0010604//positive regulation of macromolecule metabolic process; GO:0010646//regulation of cell communication; GO:0010647//positive regulation of cell communication; GO:0010799//regulation of peptidyl-threonine phosphorylation; GO:0010800//positive regulation of peptidyl-threonine phosphorylation; GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway; GO:0010941//regulation of cell death; GO:0016042//lipid catabolic process; GO:0016310//phosphorylation; GO:0019219//regulation of nucleobase-containing compound metabolic process; GO:0019220//regulation of phosphate metabolic process; GO:0019222//regulation of metabolic process; GO:0019722//calcium-mediated signaling; GO:0019751//polyol metabolic process; GO:0019932//second-messenger-mediated signaling; GO:0022603//regulation of anatomical structure morphogenesis; GO:0023051//regulation of signaling; GO:0023052//signaling; GO:0023056//positive regulation of signaling; GO:0030148//sphingolipid biosynthetic process; GO:0030149//sphingolipid catabolic process; GO:0030258//lipid modification; GO:0030307//positive regulation of cell growth; GO:0030334//regulation of cell migration; GO:0030335//positive regulation of cell migration; GO:0031323//regulation of cellular metabolic process; GO:0031325//positive regulation of cellular metabolic process; GO:0031326//regulation of cellular biosynthetic process; GO:0031396//regulation of protein ubiquitination; GO:0031398//positive regulation of protein ubiquitination; GO:0031399//regulation of protein modification process; GO:0031401//positive regulation of protein modification process; GO:0032268//regulation of cellular protein metabolic process; GO:0032270//positive regulation of cellular protein metabolic process; GO:0032501//multicellular organismal process; GO:0032502//developmental process; GO:0032870//cellular response to hormone stimulus; GO:0032879//regulation of localization; GO:0033993//response to lipid; GO:0034311//diol metabolic process; GO:0034312//diol biosynthetic process; GO:0034641//cellular nitrogen compound metabolic process; GO:0035556//intracellular signal transduction; GO:0040008//regulation of growth; GO:0040012//regulation of locomotion; GO:0040017//positive regulation of locomotion; GO:0042127//regulation of cell proliferation; GO:0042221//response to chemical; GO:0042325//regulation of phosphorylation; GO:0042327//positive regulation of phosphorylation; GO:0042981//regulation of apoptotic process; GO:0043066//negative regulation of apoptotic process; GO:0043067//regulation of programmed cell death; GO:0043069//negative regulation of programmed cell death; GO:0044057//regulation of system process; GO:0044093//positive regulation of molecular function; GO:0044237//cellular metabolic process; GO:0044238//primary metabolic process; GO:0044242//cellular lipid catabolic process; GO:0044248//cellular catabolic process; GO:0044249//cellular biosynthetic process; GO:0044255//cellular lipid metabolic process; GO:0044271//cellular nitrogen compound biosynthetic process; GO:0044281//small molecule metabolic process; GO:0044283//small molecule biosynthetic process; GO:0045765//regulation of angiogenesis; GO:0045766//positive regulation of angiogenesis; GO:0045787//positive regulation of cell cycle; GO:0045927//positive regulation of growth; GO:0045931//positive regulation of mitotic cell cycle; GO:0045933//positive regulation of muscle contraction; GO:0045937//positive regulation of phosphate metabolic process; GO:0045987//positive regulation of smooth muscle contraction; GO:0046165//alcohol biosynthetic process; GO:0046173//polyol biosynthetic process; GO:0046466//membrane lipid catabolic process; GO:0046467//membrane lipid biosynthetic process; GO:0046512//sphingosine biosynthetic process; GO:0046519//sphingoid metabolic process; GO:0046520//sphingoid biosynthetic process; GO:0046521//sphingoid catabolic process; GO:0046834//lipid phosphorylation; GO:0048145//regulation of fibroblast proliferation; GO:0048146//positive regulation of fibroblast proliferation; GO:0048518//positive regulation of biological process; GO:0048519//negative regulation of biological process; GO:0048522//positive regulation of cellular process; GO:0048523//negative regulation of cellular process; GO:0048583//regulation of response to stimulus; GO:0048584//positive regulation of response to stimulus; GO:0048856//anatomical structure development; GO:0050789//regulation of biological process; GO:0050793//regulation of developmental process; GO:0050794//regulation of cellular process; GO:0050896//response to stimulus; GO:0051090//regulation of sequence-specific DNA binding transcription factor activity; GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051092//positive regulation of NF-kappaB transcription factor activity; GO:0051094//positive regulation of developmental process; GO:0051128//regulation of cellular component organization; GO:0051171//regulation of nitrogen compound metabolic process; GO:0051173//positive regulation of nitrogen compound metabolic process; GO:0051174//regulation of phosphorus metabolic process; GO:0051239//regulation of multicellular organismal process; GO:0051240//positive regulation of multicellular organismal process; GO:0051246//regulation of protein metabolic process; GO:0051247//positive regulation of protein metabolic process; GO:0051252//regulation of RNA metabolic process; GO:0051270//regulation of cellular component movement; GO:0051272//positive regulation of cellular component movement; GO:0051716//cellular response to stimulus; GO:0051726//regulation of cell cycle; GO:0060255//regulation of macromolecule metabolic process; GO:0060548//negative regulation of cell death; GO:0060759//regulation of response to cytokine stimulus; GO:0065007//biological regulation; GO:0065009//regulation of molecular function; GO:0070887//cellular response to chemical stimulus; GO:0071215//cellular response to abscisic acid stimulus; GO:0071229//cellular response to acid chemical; GO:0071310//cellular response to organic substance; GO:0071396//cellular response to lipid; GO:0071495//cellular response to endogenous stimulus; GO:0071704//organic substance metabolic process; GO:0080090//regulation of primary metabolic process; GO:0090257//regulation of muscle system process; GO:0090351//seedling development; GO:0090520//sphingolipid mediated signaling pathway; GO:0097164//ammonium ion metabolic process; GO:0097305//response to alcohol; GO:0097306//cellular response to alcohol; GO:1901222//regulation of NIK/NF-kappaB signaling; GO:1901224//positive regulation of NIK/NF-kappaB signaling; GO:1901342//regulation of vasculature development; GO:1901564//organonitrogen compound metabolic process; GO:1901565//organonitrogen compound catabolic process; GO:1901566//organonitrogen compound biosynthetic process; GO:1901575//organic substance catabolic process; GO:1901576//organic substance biosynthetic process; GO:1901615//organic hydroxy compound metabolic process; GO:1901617//organic hydroxy compound biosynthetic process; GO:1901700//response to oxygen-containing compound; GO:1901701//cellular response to oxygen-containing compound; GO:1902531//regulation of intracellular signal transduction; GO:1902533//positive regulation of intracellular signal transduction; GO:1903320//regulation of protein modification by small protein conjugation or removal; GO:1903322//positive regulation of protein modification by small protein conjugation or removal; GO:1903506//regulation of nucleic acid-templated transcription; GO:1904018//positive regulation of vasculature development; GO:2000026//regulation of multicellular organismal development; GO:2000112//regulation of cellular macromolecule biosynthetic process; GO:2000145//regulation of cell motility; GO:2000147//positive regulation of cell motility; GO:2001141//regulation of RNA biosynthetic process | GO:0000325//plant-type vacuole; GO:0005575//cellular_component; GO:0005622//intracellular; GO:0005623//cell; GO:0005634//nucleus; GO:0005737//cytoplasm; GO:0005773//vacuole; GO:0005774//vacuolar membrane; GO:0005829//cytosol; GO:0005886//plasma membrane; GO:0009705//plant-type vacuole membrane; GO:0016020//membrane; GO:0031090//organelle membrane; GO:0043226//organelle; GO:0043227//membrane-bounded organelle; GO:0043229//intracellular organelle; GO:0043231//intracellular membrane-bounded organelle; GO:0044422//organelle part; GO:0044424//intracellular part; GO:0044437//vacuolar part; GO:0044444//cytoplasmic part; GO:0044446//intracellular organelle part; GO:0044464//cell part; GO:0071944//cell periphery; GO:0098588//bounding membrane of organelle; GO:0098805//whole membrane | GO:0000166//nucleotide binding; GO:0000287//magnesium ion binding; GO:0001727//lipid kinase activity; GO:0003674//molecular_function; GO:0003676//nucleic acid binding; GO:0003677//DNA binding; GO:0003824//catalytic activity; GO:0004888//transmembrane signaling receptor activity; GO:0004930//G-protein coupled receptor activity; GO:0005488//binding; GO:0005515//protein binding; GO:0005516//calmodulin binding; GO:0005524//ATP binding; GO:0005543//phospholipid binding; GO:0008144//drug binding; GO:0008289//lipid binding; GO:0008481//sphinganine kinase activity; GO:0016301//kinase activity; GO:0016740//transferase activity; GO:0016772//transferase activity, transferring phosphorus-containing groups; GO:0016773//phosphotransferase activity, alcohol group as acceptor; GO:0017050//D-erythro-sphingosine kinase activity; GO:0017076//purine nucleotide binding; GO:0019899//enzyme binding; GO:0019902//phosphatase binding; GO:0019903//protein phosphatase binding; GO:0030554//adenyl nucleotide binding; GO:0032553//ribonucleotide binding; GO:0032555//purine ribonucleotide binding; GO:0032559//adenyl ribonucleotide binding; GO:0035639//purine ribonucleoside triphosphate binding; GO:0036094//small molecule binding; GO:0038023//signaling receptor activity; GO:0038036//sphingosine-1-phosphate receptor activity; GO:0043167//ion binding; GO:0043168//anion binding; GO:0043169//cation binding; GO:0045125//bioactive lipid receptor activity; GO:0046872//metal ion binding; GO:0051721//protein phosphatase 2A binding; GO:0060089//molecular transducer activity; GO:0070300//phosphatidic acid binding; GO:0097159//organic cyclic compound binding; GO:0097367//carbohydrate derivative binding; GO:1901265//nucleoside phosphate binding; GO:1901363//heterocyclic compound binding

KEGG

K04718 | SPHK

NR

RWR93600.1 Diacylglycerol kinase [Cinnamomum micranthum f. kanehirae]

Swiss-Prot

F2Y4A3.1 RecName: Full=Sphingosine kinase 2 [Arabidopsis thaliana]